This course is designed for practitioners and those who are either participants in facilitated layer of protection analysis (LOPA) or simply want a better understanding. It covers all facets of performing LOPA. It lays the foundation with basic probability math and event tree analysis, as well as topics on human error and common mode failure. The transition to LOPA from a basic HAZOP is covered, considering the impact of corporate risk criteria. Initiating causes, enabling events, independent layers of protection, and conditional modifiers are all covered. To drive the methodology home, hands on workshops are conducted.